Cytoprotective effect of Centaurea solstitiulis extracts on gastric lesions induced by stress in rats
Keywords:
Centaurea solstitialis, Flavonoids, Sesquiterpene lactonesAbstract
Residues aqueous, methanolic and chloroformic extracts of Centaurea solstüialis L. Compositae flowers, commonly known as Abrepuño, were resuspended with an excipient mixture of Tween 80 (T80) and Carboxymethyl cellulose (CMC) and administered through a gastric catheter to female Wistar rats in order to study the citoprotective properties ofthe plant on ulcers caused by stress due to immersion in water. The essay were carried out by administering T80 + CMC to a group of five rats as control. Other four groups, of equal number of animals, were treated with aqueous (a), methanolic (b), methanolic-chloroformic (1:1) (c) and chloroformic residues,a ll of them resuspendedin a mixture of T80 + CMC. Prevention to ulcers in a, c and d groups was 100%, whereas a 78%o was reached in grou b (p0.05). The methanolic and chloroformic extracts, which contain flavonoid and sesquiterpenela ctonesr espectively, would be responsiblef or the citoprotective effects shown by these results.Downloads
Downloads
Published
How to Cite
Issue
Section
License
Al momento de enviar sus contribuciones, los colaboradores deberán declarar , de manera fehaciente, que poseen el permiso del archivo o repositorio donde se obtuvieron los documentos que se anexan al trabajo, cualquiera sea su formato (manuscritos inéditos, imágenes, archivos audiovisuales, etc.), permiso que los autoriza a publicarlos y reproducirlos, liberando a la revista y sus editores de toda responsabilidad o reclamo de terceros , los autores deben adherir a la licencia Creative Commons denominada “Atribución - No Comercial CC BY-NC-SA”, mediante la cual el autor permite copiar, reproducir, distribuir, comunicar públicamente la obra y generar obras derivadas, siempre y cuando se cite y reconozca al autor original. No se permite, sin embargo, utilizar la obra con fines comerciales.